Research Activities

Our research activities cover seven cross cutting research themes and hubs and focus on head and neck, bladder, prostate, cervix, lung cancers, along with paediatric cancers and lymphomas. Find out more about the research activities in RadNet Manchester and the academic and project manager teams helping to deliver our vision.

Research work packages and cross-cutting research hubs of the CRUK RadNet Manchester. At the core of RadNet are four research hubs: Proton Biology, clinical informatics, translational and early phase trials, AHP Doctoral Academy. Supporting this are three work packages: Co-morbidity research, radiotherapy and immuno-oncology cell interactions and genetics and the tumour microenvironment and hypoxia.

The three key research work packages and the corresponding cross-cutting research hubs that lie at the heart of CRUK RadNet Manchester.

A matrix of the research work packages and hubs and the disease sites being activated in the theme. Radiotherapy and immune cells - Lung, Bladder & Prostate, CNS, Lymphoma, Head and Neck. Therapeutics and comorbidities - Lung, Bladder & Prostate, Head and Neck. Genomics and TME-Hypoxia - - Lung, Bladder & Prostate, Cervix, CNS, Lymphoma, Head and Neck. Proton Biology -- Lung, Paediatric cancer, CNS, Head and Neck. Translational Biomarkers and Early Trials - - Lung, Paediatric cancer, Bladder & Prostate, Cervix, CNS, Lymphoma, Head and Neck.

A disease site, research work package/ cross-cutting research hub matrix showing the priority tumour sites for RadNet Manchester.

About RadNet Manchester Research Activities (PDF, 475KB)

Cancer Research UK RadNet Manchester research aims to integrate biological and clinical data for Manchester patients treated with radiotherapy and are supported by collaborative hubs for uplifting personnel and maximising clinical impact. Discover the impressive work taking place across our seven themes through the links below.


Radiotherapy and Immune Cell Interactions

Discover research investigating the immunological consequences of radiotherapy, including immunotherapy and radiotherapy combinations.

Treating Complex Comorbid Patients

Discover how we are working to understand the mechanisms of the most common and detrimental side effects of radiotherapy, and how these are influenced by medications or conditions in a patients life.

Tumour Microenvironment and Genetic Instability

Discover research in RadNet Manchester aiming to improve understanding of intra-tumour heterogeneity, radioresistance and metastasis.

National Proton Beam Therapy Hub

Discover how we are leveraging cutting edge infrastructure in Manchester to develop new treatments involving proton beam therapy.

Clinical Informatics Hub

Discover how this hub supports the capture, storage and use of routine real-time, real-world clinical outcomes to inform future research.

Translational and Early Phase Radiotherapy Trials Hub

Discover how we provide the support and translational research expertise to integrate biomarker science into the development of phase one feasibility studies.

AHP Doctoral Academy

Providing training and development for Allied Health Professionals (AHPs) including radiographers.

About CRUK RadNet Manchester

CRUK RadNet Manchester is a £16.5m Radiation Research Unit in collaboration with The Christie

RadNet Facilities and Infrastructure

CRUK RadNet Manchester benefits from the existing infrastructure and facilities within Manchester across the various strategic partners of the CRUK Manchester Centre.