STRIPE: STandardised Reporting of Imaging to assess the Postmenopausal Endometrium

Closing date: 15/03/2027

MB-PhD Studentship: STRIPE: STandardised Reporting of Imaging to assess the Postmenopausal Endometrium

Lead Supervisors: Professor Emma Davidson
Lead Supervisors: Dr Eleanor Jones, Dr Jamie Sergeant, Dr Caroline Sanders

Applications Deadline: Monday 15th March 2027
Interviews: Week commencing 3rd May 2027
Start date: September 2027

Project Keywords: Endometrial cancer, postmenopausal bleeding, transvaginal ultrasound
Research Opportunity: MB-PhD Studentship

Project Outline

Postmenopausal bleeding (PMB) is the red-flag symptom for endometrial cancer. It affects over 200,000 women in the UK every year, but fewer than 5% of these women have cancer, meaning the majority undergo unnecessary invasive investigations. Current triage relies on transvaginal ultrasound (TVS) measurement of endometrial thickness, with women measuring ≥4mm referred for endometrial biopsy and/or hysteroscopy. However, variation in endometrial thickness measurement and ultrasound reporting may affect diagnostic accuracy and contribute to inequalities in care.

The STRIPE study (STandardised Reporting of Imaging to assess the Postmenopausal Endometrium) will investigate how consistently healthcare professionals assess and report the endometrium in women with PMB and develop a standardised reporting proforma. Ultrasound scans obtained from the national multicentre SONNET study will undergo independent external review by experienced radiologists and sonographers. Interobserver agreement will be assessed by comparing the endometrial thickness on review with the original clinical measurement, and analysed across subgroups, including women with endometrial thickness 3-5mm, different ethnic backgrounds, hormone replacement use, body mass index and underlying pathology.

We will also investigate whether other ultrasound features may help identify women who are more likely to have endometrial cancer. The study will use these findings to develop a standardised ultrasound reporting proforma. A consensus process involving ultrasound and gynaecology experts, alongside patient and public contributors, will help determine which features should be routinely assessed and reported. STRIPE is part of the wider SONNET research programme, which aims to improve the diagnosis of endometrial cancer in women with PMB.

Ultimately, STRIPE aims to make ultrasound assessment more consistent and reliable, helping clinicians make better-informed decisions about which women need further investigation. This could reduce unnecessary invasive procedures for women who do not have cancer while supporting earlier and more accurate diagnosis for those who do.

Applications for this project are now open. Please complete your application on The University of Manchester Postgraduate Application Portal.

About Prof. Emma Davidson (project Lead Supervisor)

Emma is a Professor of Gynaecological Oncology whose research interests include screening, prevention and the early detection of gynaecological cancers, as well as developing new treatments and interventions for women with established disease.

In 2023, Emma was awarded a Lynch Syndrome UK personal award for Services to People with Lynch syndrome. In 2024, she won FindAPhD Postgraduate Supervisor of the Year and was awarded a prestigious NIHR Research Professorship. In the same year, her team won the American Association of Cancer Research Team Science Award and were Highly Commended in the University of Manchester Making A Difference Awards for Outstanding Benefit to Inclusive Research.

Find out more

Emma Davidson headshot

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