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CRUK Major Centre PhD projects

 

Our PhD programmes are highly competitive. We seek motivated students looking to develop further experience in oncology and have the drive and ambition to transalte novel research into patient benefit.

Within the Centre, we offer:

  • Non-Clinical PhD Studentships for recent graduates to undertake an exciting PhD programme, funded by the Cancer Research UK Manchester Centre, or CRUK RadNet Manchester.
  • Clinical Research Training Fellowships for clinicians looking to undertake full-time research training. This includes collaborative CRTFs with the University of Leeds centred on clinical trials or academic pathology.
  • MB-PhDs for University of Manchester MB-ChB student to gain an integrated cancer sciences PhD within their clinical training.
  • Allied Health Professional Research Radiographer PhDs, funded by CRUK RadNet Manchester

Prior to beginning an application, interested applicants should check the following:

Follow these link to find the last opportunities for:

 


Non-Clinical PhD Studentship Opportunities 

Opportunities for our Non-Clinical PhD Studentships are now open, please find a list of projects below. The deadline for applications is Sunday the 29th of November.

For our CRUK Manchester Centre PhD schemes, formal applications should be submitted via The University of Manchester application portal, this will include adding your CV, name and contact details for referees and a personal statement (1000 words max). Please also comment on your suitability for the post, giving an overview of your relevant experience and training.

Projects available for applications are listed below.

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships
Project Title: Investigating the role of LGALS1 as a novel therapeutic target in CMML
Primary Supervisor: Dr Kiran Batta
Additional Supervisors: Dr Daniel Wiseman and Professor Tim Somervaille
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships
Project Title: Deconvoluting the epigenetic transition and intratumour heterogeneity in aggressive breast cancers
Primary Supervisor: Dr Sankari Nagarajan
Additional Supervisors: Professor Andrew Sharrocks, Professor Rob Clarke, and Dr Anne Armstrong
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships
Project Title: Oncogenic signalling through transcriptional repression pathways in oesophageal adenocarcinoma
Primary Supervisor: Professor Andrew Sharrocks
Additional Supervisors: Professor Ang Yeng
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships
Project Title: High dimensional spatial analysis of the tumour microenvironment and the immune response within brain tumours
Primary Supervisor: Dr Kevin Couper
Additional Supervisors: Professor Frederico Roncaroli, Professor David Brough, Dr David Coope, and Dr Omar Pathmanaban
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships​
Project Title: Range verification in proton beam therapy through prompt gamma-ray imaging
Primary Supervisor: Dr Michael Taylor
Additional Supervisors: Professor Ranald Mackay
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships​
Project Title: Targeting heat shock protein 90 (HSP90) to overcome adaptive resistance mediated by the PD-L1 immune checkpoint
Primary Supervisor: Dr Jamie Honeychurch
Additional Supervisors: Professor Ananya Choudhury
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships​
Project Title: Using ex vivo models to determine early transcriptome changes in breast cancer
Primary Supervisor: Professor Keith Brennan
Additional Supervisors: Dr Andrew Gilmore, Dr Ahmet Ucar, and Dr Sacha Howell  
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Non-Clinical PhD Studentships​
Project Title: Bioenergetic vulnerabilities of pancreatic cancer during the cell cycle: Role of the glycolytic enzyme, pyruvate kinase-M2 (PKM2) 
Primary Supervisor: Dr Jason Bruce
Additional Supervisors: Professor Kaye Williams, Dr Claus Jorgensen and Professor Juan Valle
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK RadNet Manchester Funded - Non-Clinical PhD Studentships​
Project Title: Transforming Radiotherapy in a Flash
Primary Supervisor: Professor Karen Kirkby
Additional Supervisors: Professor Neil Burnet, Dr Michael Merchant, Dr Amy Chadwick, Dr Elham Santina
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 


Clinical Research Training Fellowship Opportunities 

Opportunities for our Clincial Research Training Fellowships are now open, please find a list of projects below. The deadline for applications is Sunday the 29th of November.

For our CRUK Major Centre PhD schemes, formally applications should be submitted via The University of Manchester application portal, this will include adding your CV, name and contact details for referees and a personal statement (1000 words max). Please also comment on your suitability for the post, giving an overview of your relevant experience and training.

Projects available for applications are listed below.

 

Cancer Research UK Manchester Centre Funded - Clinical Research Training Fellowship
Project Title: Creating and annotating a digital pathology atlas for primary and metastatic PDA
Primary Supervisor: Dr Claus Jorgensen
Additional Supervisors: Professor Ged Brady and Professor Juan Valle
Duration: 4 years
Expected Start Date: April 2021 onwards
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Clinical Research Training Fellowship
Project Title: Developing circulating and imaging biomarkers towards personalised radiotherapy in lung cancer
Primary Supervisor: Professor Corinne Faivre-Finn
Additional Supervisors: Professor Caroline Dive and Dr Gareth Price
Duration: 3 years
Expected Start Date: April 2021 onwards
Find out more information about the project here
​Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Clinical Research Training Fellowship
Project Title: Decreasing the risk of arm and shoulder problems after breast cancer ​
Primary Supervisor: Dr Marianne Aznar
Additional Supervisors: Dr Camel Anandadas, Professor Nigel Bundred and Professor Janelle Yorke
Duration: 3 years
Expected Start Date: April 2021 onwards
Find out more information about the project here
Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Manchester Centre Funded - Clinical Research Training Fellowship
Project Title: Imaging and biological markers of sarcopenia development in frail, multimorbid patients
Primary Supervisor: Dr Andrew Green
Additional Supervisors: Dr Alan McWilliam, Professor Ananya Choudhury and Dr Tim Smith
Duration: 3 years
Expected Start Date: April 2021 onwards
Find out more information about the project here
Submit your application via the University of Manchester application page here (external page link).

 

Cancer Research UK Leeds-Manchester Centre Funded - Clinical Research Training Fellowship
Project Title: Rationally developing the next generation of personalised target drug-chemotherapy combination trials in anal cancer
Primary Supervisor: Dr Adel Samson, University of Leeds
Additional Supervisors: Professor David Sebag-Montefiore, Dr Sarah Brown, Dr Natalie Cook and Professor Andrew Renehan
Duration: 3 years
Expected Start Date: 1st September 2021
Find out more information about the project here
Submit your application via the University of Leeds page here (external page link).

 


MB-PhD projects

Applications for our MB-PhD training schemes are now open for application.

The deadline for applications for our MB-PhD projects is the 5th March 2021.

Before submitting you application make sure you have read the MB-PhD Application Guidance document (PDF, 346KB) that details eligibility, funding and timelines for projects. Projects available for applications are listed below.

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Using AI for risk prediction and early detection of breast cancer
Primary Supervisor: Professor Sue Astley
Additional Supervisors: Dr Sacha Howell, Dr Yit Yoong Lim and Dr Martin Fergie
Duration: 3 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Mapping the transcriptional repressive enviornment of oesophageal adenocarcinoma: implications for oncogenic signalling outcomes
Primary Supervisor: Professor Andy Sharrocks
Additional Supervisors: Professor Ang Yeng and Dr Was Mansoor
Duration: 3 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Novel therapeutic strategies for ovarian cancer
Primary Supervisor: Professor Stephen Taylor
Additional Supervisors: Dr Natalie Cook, Dr Richard Unwin and Dr Anthony Tighe
Duration: 3 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Deciphering evolution of small cell lung cancer from diagnosis to post chemotherapy disease progression: a search for new drug targets
Primary Supervisor: Professor Caroline Dive, CBE
Additional Supervisors: Professor Fiona Blackhall, Dr Kris Frese and Dr Alistair Kerr
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Investigation of the pro-tumour microenvironment of CNS (brain and leptomeningeal) metastasis in secondary breast cancer
Primary Supervisor: Professor Robert Clarke
Additional Supervisors: Dr Ciara O'Brien and Professor Frederico Roncaroli
Duration: 3 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Understanding resistance to preventative tamoxifen therapy in women at high risk of breast cancer
Primary Supervisor: Dr Andrew Gilmore
Additional Supervisors: Dr Sacha Howell and Dr Joe Swift
Duration: 3 years
Expected Start Date: 1st October 2021
Find out more information about the project here

 

Cancer Research UK Clinical Academic Training Award Funded - MB-PhD
Project Title: Microenvironmental regulation of malignant blood clones in myelofibrosis
Primary Supervisor: Professor Tim Somervaille
Additional Supervisors: Dr Claus Jørgensen
Duration: 4 years
Expected Start Date: 1st October 2021
Find out more information about the project here

If you have any queries with this process, please contact Dr Georgina Binnie at mcrctraining@manchester.ac.uk.


 

Allied Health Professional Research Radiographer PhDs

Thanks to funding from CRUK Manchester RadNet, we now offer three-year, high-quality research projects supervised by core members of the Allied Health Professions (AHP) Academic Hub, colleagues from the Radiotherapy Related Research (RRR) group and the Manchester Cancer Research Centre (MCRC). These include an appropriate salary match, PhD fees at the UK rate and running costs/consumables. Queries can be directed to Cynthia Eccles, Head of Radiotherapy Research and Development at The Christie NHS Foundation Trust: cynthia.eccles1@nhs.net.